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Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging Volume 1 – 7][UnitedVRG][PDF]

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  Autophagy: Cancer, Other Pathologies, Inflammation,
Immunity, Infection, and Aging, 1st Edition [Volume 1 – 7]
  
  by M HAYAT (Editor)
  
   
  
  •	Pages: Various Books
  
  •	Publisher: Academic Press
(2013/2014/2015)
  
  •	Language: English
  
  •	ISBN-13:
9780124055308/9780124058774/9780124055292/9780124055285/9780128010334/9780128010327/9780128010433
  
 
Description
  
  Autophagy:
Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is a complete, authoritative examination of
the role of autophagy in health and disease. Understanding this phenomenon is vital for the studies of cancer, aging,
neurodegeneration, immunology, and infectious diseases. Comprehensive and forward thinking, this four-volume work offers
a valuable guide to cellular processes while encouraging researchers to explore their potentially important
connections.
  
  Understanding the role of autophagy is critical, considering its association with numerous
biological processes, including cellular development and differentiation, cancer (both antitumor and protumor
functions), immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and
degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases.
Cell homeostasis is achieved by balancing biosynthesis and cellular turnover. In spite of the increasing importance of
autophagy in various pathophysiological conditions mentioned above, this process remains underestimated and overlooked.
As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases (e.g.,
autoimmune disease) remains poorly understood.
  
  This work will broaden the knowledge base of academic and
clinical professors, post-doctoral fellows, graduate and medical students regarding this vital biological process.

 
  Key Features
  
  •	Presents the most advanced information regarding the role of the
autophagic system in life and death and whether autophagy acts fundamentally as a cell survivor or cell death pathway,
or both
  
  •	Introduces new, more effective therapeutic strategies in the development of targeted
drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation
  
  •	Covers recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic
diseases and abnormalities
  
  Volumes in the Series
  
  Volume 1: Molecular
Mechanisms. Elucidates autophagy’s association with numerous biological processes, including cellular
development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis,
response to cellular stress, and degenerative diseases such as Alzheimer’s, Parkinson's, Huntington's,
amyotrophic lateral sclerosis, and prion diseases.
   
  Volume 2: Role in General Diseases. Describes
the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a
discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general
diseases. 
   
  Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific
diseases and developments, including: Crohn’s Disease, Gaucher Disease, Huntington’s Disease, HCV
infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor
development and cancer, as well as the relationship between autophagy and apoptosis.
  
  Volume 4:
Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in
health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and
execution, as well as the role of mitophagy in Parkinson Disease, cardiac aging, and skeletal muscle atrophy.
  

  Volume 5: Role in Human Diseases. Comprehensively describes the role of autophagy in human diseases,
delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer;
and the duality of autophagy’s effects in various cardiovascular, metabolic, and neurodegenerative disorders.
  
  Volume 6: Regulation of Autophagy and Selective Autophagy. Provides coverage of the mechanisms of
regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity;
and selective autophagy. 
  
  Volume 7: Role of Autophagy in Therapeutic Applications. Provides
coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality
control; the role of autophagy in apoptosis; autophagy in the cardiovascular system; and the relationships between
autophagy and lifestyle. 						

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